Tuberculosis Skin Test Screening in the National Tuberculosis Program of Trinidad and Tobago

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dc.contributor.authorChattu, Vijay Kumar
dc.contributor.authorSakhamuri, Sateesh
dc.contributor.authorMotilal, Shastri
dc.contributor.authorPounder, Liam J.
dc.contributor.authorPersad, Vasishma Kanita
dc.contributor.authorPierre, Neelmani
dc.contributor.authorPersad, Shivannie
dc.contributor.authorPooran, Nikesha
dc.contributor.authorPottinger, Akua Mosi
dc.date.accessioned2021-09-21T17:52:44Z
dc.date.available2021-09-21T17:52:44Z
dc.date.issued2020
dc.description.abstractGlobally, a quarter of the population is infected with tuberculosis (TB), caused by Mycobacterium tuberculosis. About 5–10% of latent TB infections (LTBI) progress to active disease during the lifetime. Prevention of TB and treating LTBI is a critical component of theWorld Health Organization’s (WHO) End TB Strategy. This study aims to examine the screening practices for prevention and treatment employed by the National Tuberculosis Program of Trinidad and Tobago in comparison to the WHO’s standard guidelines. A cross-sectional retrospective study was conducted from the TB registers (2018–2019) for persons aged 18 years and above with recorded tuberculin skin test reactions (TST). Bivariate comparisons for categorical variables were made using Chi-square or Fisher’s exact test. Binary logistic regression was used for exploring predictors of TST positivity with adjustment for demographic confounders in multivariable models. Of the total 1972 eligible entries studied, 384 (19.4%) individuals were tested positive with TST. TB contact screening (aOR 2.49; 95% CI 1.65, 3.75) and Bacillus Calmette–Guerin (BCG) vaccination status (aOR 1.66; 95% CI, 1.24 to 2.22) were associated with a positive TST reaction, whereas, preplacement screening failed to show such association when compared to those screened as suspect cases. The findings suggest that TB contact screening and positive BCG vaccination status are associated with TST positivity independent of age and genderen_US
dc.identifier.citationChattu, V.K.; Sakhamuri, S.; Motilal, S.; Pounder, L.J.; Persad, V.K.; Pierre, N.; Persad, S.; Pooran, N.; Pottinger, A.M. Tuberculosis Skin Test Screening in the National Tuberculosis Program of Trinidad and Tobago. Healthcare 2020, 8, 236. https://doi.org/10.3390/healthcare8030236en_US
dc.identifier.issn2227-9032
dc.identifier.urihttps://www.mdpi.com/2227-9032/8/3/236
dc.identifier.urihttps://hdl.handle.net/2139/49736
dc.language.isoenen_US
dc.publisherHealthcareen_US
dc.relation.ispartofseries;Volume 8 Issue 3
dc.subjectMycobacterium tuberculosisen_US
dc.subjectWorld Health Organization (WHO)en_US
dc.subjectLatent TB infection (LTB)en_US
dc.subjectTuberculin skin test (TST)en_US
dc.subjectBacillus Calmette–Guerin (BCG)en_US
dc.subjectInterferon-Gamma releasing assays (IGRAs)en_US
dc.subjectTrinidad and Tobagoen_US
dc.titleTuberculosis Skin Test Screening in the National Tuberculosis Program of Trinidad and Tobagoen_US
dc.typeArticleen_US

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