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Item Assessment of chemopreventive and anti-cancer value of artocarpus heterophyllus LAM, in colorectal cancer(2022) Morrison, Isaac JayItem Examining inclusive education at a private school in urban Jamaica: a single case study(2022) Leachman, Kishi Emeshia AndersonItem Biochemical comparison of white yam biomaterials and novel synthesized anticancer compounds(2022) Wallace, Kenroy KimarItem Detection and diversity of select sweet potato viruses in two Caribbean countries, Jamaica and Trinidad and Tobago(2022) Johnson, Lloyd GeorgeItem Adequate housing in Jamaica : the perspectives of householders and housing planners(2021) Jackson, AnetheoItem Towards a restorative reentry framework: supporting desistance from crime and enhancing re/integration(2022) Simpson, Joanna Nicole AbigailItem The coral reef health and water quality of the inshore and offshore Port Royal reefs, Jamaica(2022) Coore, KimberleyItem Spiritual assemblages : revival, dress, ritual and power(2022) Henry, Kirt OrlandoItem The culture and propagation of a novel Jamaican prostate cell line(2020) Valentine, Henkel LeeItem Immunometabolism in cardiovascular disease and diabetes mellitus during treated HIV infection(2022) Butterfield, Tiffany RoxanneImmunometabolism in cardiovascular disease and diabetes mellitus during treated HIV infection Tiffany Roxanne Butterfield Cardiovascular disease (CVD) and diabetes mellitus (DM) have become prevalent co-morbidities for persons living with HIV (PLWH) in high income countries. Both diseases are associated with chronic inflammation and immune activation in treated PLWH, with monocytes and T cells suggested to be important contributors of inflammation. Elevated glucose metabolism in monocytes and T cells is linked to inflammatory functions, but the role of heightened glucose metabolism in immune cells in PLWH with CVD or DM is unknown. HIV+ participants from the Women’s Interagency HIV Study (WIHS) cohort were selected by the presence of subclinical CVD or DM and matched to controls. HIV+ women with DM showed evidence of increased glucose metabolism in CD4+ T cells compared to HIV+ women without DM and HIV‒ women with DM. In HIV+ women with subclinical CVD there was evidence of increased glucose metabolism in intermediate monocytes compared to HIV+ women without subclinical CVD. These results suggest that immunometabolism in PLWH may be a contributing factor towards DM and CVD. Whether these results are also applicable in a low- and middle-income country (LMIC) setting is uncertain. Accordingly, the prevalence of CVD risk in HIV+ participants enrolled at the CHARES clinic of the UHWI in Jamaica was assessed by measuring HDL cholesterol concentration. Most participants had intermediate high risk of CVD at enrolment and intermediate risk of CVD at 3-years post enrolment. HIV+ males were more likely to be classified as high risk and this was associated with high viral load and low CD4 count at 3-years post enrolment. In summary, immunometabolism was associated with CVD and DM in PLWH in a high income setting and the identification of CVD being prevalent in HIV+ Jamaicans warrants additional investigation to determine if immunometabolism is also relevant to CVD in a LMIC context. Keywords: HIV, immunometabolism, cardiovascular disease, diabetes mellitus, monocytes, CD4+ T cells.Item Energy expenditure, adiposity and cardiovascular risk in urban and rural Jamaican adultsCargill, Kathryn ElizabethItem A morphological and molecular survey of Gambusia sp. in certain Jamaica riversBennett, Kerri-Ann LaliqueItem History and the politics of representing black women in Anglophone fiction in post-colonial AmericasSmith, Yvonne Valda BlagroveItem Early life predictors of dietary intake and physical activity in Afro-Jamaica childrenCampbell, Claudia PatriciaItem Towards a framework for national e-learning implementation : a Jamaican case studyCharlton-Laing, ChristineItem A review (2005-2010) of the tuberculosis programme in the Western Region, JamaicaStennett, Dianne CampbellItem Understanding Caribbean identity and its implications on Caribbean economic developmentConnell, Khimaja Ramoy