Browsing by Author "Liang, Tiebing"

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    Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDHIAI*4
    (2009-07-01) Moore, Shelley M; Liang, Tiebing; Graves, Tamara J; McCall, Kevin M; Carr, Lucinda G; Ehlers, Cindy L
    Abstract This paper reports the identification of a novel cytosolic aldehyde dehydrogenase 1 (ALDHIAI) allele. One hundred and sixty-two Indo-Trinidadian and 85 Afro-Trinidadian individuals were genotyped. A novel ALDHIAI allele, ALDHIAI*4, was identified in an Indo-Trinidadian alcoholic with an A inserted at position -554 relative to the translational start site, +1. It was concluded that a wider cross-section of individuals needs to be evaluated in order to determine the representative frequency of the allele, and to see if it is associated with risk of alcoholism.