Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDHIAI*4

Moore, Shelley MLiang, TiebingGraves, Tamara JMcCall, Kevin MCarr, Lucinda GEhlers, Cindy L2012-07-262012-07-262009-07-01Human Genomics. 2009 Jul 01;3(4):304-307https://hdl.handle.net/2139/13141Abstract This paper reports the identification of a novel cytosolic aldehyde dehydrogenase 1 (ALDHIAI) allele. One hundred and sixty-two Indo-Trinidadian and 85 Afro-Trinidadian individuals were genotyped. A novel ALDHIAI allele, ALDHIAI*4, was identified in an Indo-Trinidadian alcoholic with an A inserted at position -554 relative to the translational start site, +1. It was concluded that a wider cross-section of individuals needs to be evaluated in order to determine the representative frequency of the allele, and to see if it is associated with risk of alcoholism.Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDHIAI*4Journal Article2012-07-26enShelley M Moore et al.; licensee BioMed Central Ltd.